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???? ???????? ??????? ???? ????? 100% ???????, ?????? ????????첩? ???? ???戟????? ???????. ????? ??????? ?????????? ??? ?? ???????! ???? ???????? ????? ??????????. ?????? ????? ???? ????? ???? ??????. ?????? ??????? ???????? ???? ????????. ???? ??????? ????? ????? ?????????.
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????? ???? ???. ????????????? ????? ???? ???? ??? ?? ??? ????? ??????. ??? ????????? ??? ?????? ?????? ?? ?? ???? ??????, ??? ?????? ???????? ?? ????? ???????? ???????.
????? ??????(Viagra) ????? ??? ????????????. ???? ???????? ??????? ????? 2013?? ??????? ????????????. ??? ???? ??? ??????? ?? ???? ?????? ???? ?????? ?? ????????. ???? ??? ???? ?? ?????????? ???????? ??? ??? ???? ??????? ???? ?????怜� ??? ???? ?????? ??????????.
???????? ??? ??????? ???? ????? ???? ?????? ????? ????????, ??? ???? ?????? ??? ?????? ?? ???? ?????? ???????? ??? ????? ??????? ????????. ????? ?????? ?????? ?? ?????????? ???????? ?????? ??????, ?洹�?? ?????? ?? ?? ?????? ????? ???? ???? ???????? ??????? ???? ??????? ??????.
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???????? ??????? ????? ????????, ????????? ??? ???? ?????? ???? ?????? ?? ??????. ???? ?????????? ???????? ?????? ??? ???? ??????? ????? ??????? ???? ???? ????. ????? ????? ??? ???쩔? ???? ??????? ?????? ?커? ??????? ???????.
??? ?????????? ???????? ?쨋??恝????? ?????? ?? ??????, ????? ???荑�?? ????????? ??????? ???????. ?쨋??恝??? ?????? ?????? ????? ?? ??? ?쨋??? ??? ???????? ???? ????? ??? ???? ???????.
???????? ?????? ??? ???? ??? ???? ?????????, ?? ?????????? ????? ??????. ???? ????? ?????????? ?????? ????? ?? ??? ?????? ???? ???????? ????????. ????? ???????? ????? ???? ???????? ??????? ???? ???? ?????? ?????? ?????? ??????.
????????????
???????? ????????? 25mg, 50mg, 100mg?? ?? ???? ?酉�???? ????????. ????? ????? ???쩔? ???岳� ???? ??怜� ????? ?酉�?? ???? ??? ?? ??????.
???? ??????? ???????? ?????? ???? 50mg?? ?酉�?? ???????, ??岳� ???? ?酉�?? ?????? ?? ??????. ????? ????? ???? ?????? ?酉�?? ??????? ??????? ????.
???????? ?????? ?? ?? 30?極??? 1?챨? ???? ???????, ????? ??? ??????? ????? ????? ?? ??????. ?????? ??????? ???? ?????? ???? ??? ????? ???? ???????. ???? ??玲� ?? ???? ??????? ???, ????? ????? ???? ?酉�?? ???????? ???? ?????? ??????? ????.
?첸????
?첸????(Tadalafil)?? ?????? ????(ED) ?? ??????????? ??? ??????? ??????. ?? ???? ???? ?????? 1991?????? ????? ???????, ???? ???????? ?????? ICOS Corporation?? ?? ???? ???? ???? ????????? ??????????.Icos Corporation?? 2007?? ???? ???? ??? ?????(Eli Lilly and Company)???? ???????????.
ICOS Corporation?? ????????? ?????? ??? ??????? ??? ?? ?荑�?? PDE5(?貫????? 5) ???????? ?????? ????? ?????????. ????? PDE5 ???????? ???? ????? ??????? ???????? ????????? ??橘????? ????????????? ?????貫轅�(cGMP)?? ?????? ??????????.
???? ICOS Corporation?? ????????? ?? ????? ?????? ???? ??? ??????? ??????????. ????? PDE5 ???????? ?????? ????? ??? ?????? ?????? ?????? ??????? ???????? ??????? ?? ???? ???? ?????????. ?? ?????, ??? ???????? ????? ?첸?????? ???????? ???????? PDE5 ?????????? ?????????, ??? ???? ??? ?????? ??????????.
??? ?????? ?첸?????? ??????? ??????? ????????? ???????????, ?????? ???? ????? ?????? ?????? ?????? ?? ?????? ??琯???????. ???? 2003?? ??? ??????(FDA)???觀??? ?????? ??? ?첸?????? ?????? ???? ??????關? ?罐? ??????? ???? ????????.
?????? ???? ?????? ????, ?첸?????? ??????????? ????? ????? ???? ???? ????????????. ??? ???? ?? ?棘???? ???? ?????? ??? ?????? ??刮?????, ??? ?慣? ??? ???? ????????.
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???????(Levitra)?? ??? ????(ED) ??? ???? ????????, ?? ???????? ?????????(Vardenafil)?? ??????? ??????. ?? ???? ?管??? ???? ????? ???? ???? ?????? ??????? ?????? ????????? ?????? ????.
????????? ??????????????(GlaxoSmithKline)?? ?????(Bayer)?? ???????? ?????? ???????. ??????? ?????????????? ?????? ??????????, ?? ?????? ?????? ??????? ???? ?????? ???????? ???????? ??? ?????? ??????????.
????????? 2003?? ??? ??????(FDA)?? ?????? ???????, ???? ????? ???????? ??????????. ??? ?????? ???? ???????? ?????? ????? ???????, ????????? ????? ???????? ??? ????? ??????? ??????.
????????? ????? ??嚥� ???? ????????? ???, ???? ???? ??? ???????? ??????? ????. ???????? ???쩔? ???????? ?????? ??????? ??????? ?????? ?酉�?? ???? ?????? ????????? ????. ????, ??????? ????? ?? ??????? ???? ?? ????? ???????.
????? ????? ???? ????? ???? ?? ??????? ??? ???????? ??????, ???? ?????? ???? ???? ???????. ????????? ???? ??? ???? ??????? ??????? ??????? ????? ????? ???? ?????? ??????? ????.
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???????(Levitra)?? ????? ??嚥� ???? ????????? ???, ???? ???? ??? ???????? ??????? ????. ????? ????????? ??????? ???? ??침????:
1. ??????? ??침?? ????????: ????????? ??????? ???? ????? ????? ?????? ????. ??怜� ??????? ?酉�?? ???? ?????? ????? ?????? ????.
2. ????? ?酉� ????: ??怜� ??????? ?酉�?? ?????????. ????????? ????? ?酉�???? ???????, ?????? ???쩔? ???? ?????? ?酉�?? ????????.
3. ????? ??? ????: ????? ??? ????????? ??????? ????? ??????? ??????. ????? ???? ????? ???? ??? ????? ???? ???????. ?????? ????? ???? ??????? ????? ???? ?? ??????.
4. ?? ???? ?챨?: ????? ????? ???? ????????? ??????? ???? ?? ???? ?챨??? ????????. ????????? ???? ??? 25~60?? ???? ??????? ???? ????????.
5. ????? ???? ???: ????????? ??????? ???? ????? ???? ?? ??????? ??? ???????? ??????. ???? ?????? ???? ???? ???????.
6. ??? ?????? ?????? ????: ??? ?????? ?????? ??????? ???????, ????????? ??????? ???? ??玲�?? ???? ???? ???? ???? ?? ?? ???????? ????????.
7. ????? ????: ??????? ???? ?? ??????? ????? ?? ???????, ???? ??????? ??玲�?? ????? ????.
????????? ??? ??? ???? ??????? ???肉� ???? ????? ?????? ??????? ?????? ???? ???? ???? ???????. ????, ??????? ??침?? ?????? ?????? ????.
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????????? ?????? ?????? ???????:
1. ??????? ??? ???? ???: ????????? ?????? ??? ?????? ?????? ?? ?????????. ??? ?????? ??????????? ?????? ??????? ?????? ???????? ??? ?????? ??????????.
2. ???? ???: ????????? ???? ??? 25~60?? ???? ??????? ?????? ????? ????? ?? ??????.
3. ???? ???? ???: ??? ?????? ????????? ?????? ?? ??? ?????? ??? 4~5?챨? ???? ????? ?? ???? ??????????.
4. ????? ??? ???? ????: ????????? ????? ??? ??????? ????? ???????? ??????. ?????? ????? ???? ?챨??? ??????? ????? ?????? ?? ??????.
5. ????? ?酉� ????: ????????? ????? ?酉�???? ??????? ????? ???쩔? ?째? ?????? ?酉�?? ?????? ?? ??????.
6. ???????? ??? ????: ????????? ??????(FDA) ???? ???????? ?????? ???????, ???????? ????? ???? ????? ?????? ??? ?????? ????????.
????? ???????? ????? ????? ????? ???? ?????? ?????? ?? ????????? ???? ??? ?????? ??????? ?????? ????.
????? ???????????? ????
????? ???? ???????????(orally disintegrating film, ODF)?? ?????? ?? ???? ?첨????? ?? ???? ?荑�?? ?????? ?? ??? ??? ?????? ??????.
???戟? Vinix
???戟??? ??????? ???? Clpharm ???? ??????? ???.???????? ??????????? ???? ?棘?? ???? ???? ?????? ODF ?????? ?????? ?????, 2003?? ????????????
???戟? ?? 1?? 1? ?????? ?? 1?챨? ???? ?????酉� 50~100mg ?????? ????????. ??? ??????? ???? ?????? ???? ???? ??? ?? ???? ???? ?荑�?? ?? ???? ??????? ????. ???戟? ????챨??? 4?챨? ???????? ??????????? ????肉� ????? ??????灌째??? ?????.
????? Sentrip
??????? ??????????????? ?????? ??? ???? ?荑�??? ????????. ????????????????20mg ?? ????? ??????? ?????? ???????? ?????? ???? ?????? ??????????館? ??? ????????? ????????.
??????? ??????? ??????? ??????, ?????????灌? ?????? 30?? ?????? ?????? ?? ??????, ??? ???? ???? ?????? 1?? 1?, ?????酉�?? 10mg ?????. ???????? ???? ?????? ???? ???커? ??? ?? ???? ???? ?荑�?? ?????? ??????? ??? ??????? ??? ?????? ?? ??????.
?????????????????????
SK?????? '?????????? 50mg'?? ????琯?, ????? '??????' ?? ???????? ???? ???? ?灌?.?징?? ???? '??????'?? ?????? ??????? ?????? ?????? ????????? ????? ???????? ????(ODF)???? ?????? ??.
ODF?? ???堉� ???????? ?????? ?????????.
?? ????????(???? ??????????? ????)?? ???? ???? ???? 16.7% ???? ?????????. ?? ????? ???? ???????.
??????? ????? ???? ??????! ????? ??????, ????? ???????
????????? ??? ?????? ???? ?????: ??????? ?????? ????
- ??????, ?? ????????? ??????? ??????
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???????? ??????? ??????? ?? ?????????? ?罐? ??????? ??????. ?????? ?쨋??恝??? ???????? ?????? ???? ????? ?????? ??? ????????. ??????? ???? ?? ???? ???? ???? ?쨋??? ??????, ??? ?????????? ??????? ??????? ???? ???? ?????? ????????. ??????? ???? ???? ?????? ????? ??????, ?????? ?????? ???? ??????? ????? ??? ?????? ???????? ?????? ?? ??????. ????, ??????? ?????? ???? ????? ?????? ???? ????? ??????? ???? ????? ??????? ????????.
????????? ?????? ???? ?? ???? ?? ???? ??
????????? ???????? ??????? ???? ?? ???? ????? ?????? ???灌? ???? ???????. ????, ???????? ????? ????? ????? ????????????. ?????? ????? ????? ???? ?? ??????? ????? ??????? ??????? ????. ??????? ???? ????? ?????? ??耳�???? ???????, ???克??? ?? ?????? ??????? ???? ????? ??? ?????? ??????. ????, ???????? ?酉�?? ?????? ??? ???쩔? ??????? ?????? ???? ????? ?? ???????, ????? ????? ????? ???? ??????? ????. ??????? ????? ?酉�?? ???????? ???????, ???? ?????? ?쨈? ?酉�?? ??????? ?????? ?? ??????.
??????????? ?????? ????? ????? ??????? ??????? ??????? ??????. ???????, ??????? ?? ????? ????? ????????? ?????? ?쨈? ???? ?????? ?? ??????. ?? ????? ?징?? ???, ????? ???? ?캉??? ?????? ??????? ??????? ???? ???????. ??????? ?? ????? ???? ????? ?????? ???????, ???? ??????? ?????? ???? ???? ???????? ??????? ??????.
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???????? ??????? ??????? ??????? ?? ???? ????????? ????? ????? ????. ????, ???????? ?????? ????? ????? ???????, ?????? ????? ??? ???? ???? ???? ???? ??????? ??? ???? ????? ????? ??????? ????. ????, ???????? ???轅� ?????? ??? ??????? ????? ???????? ?????? ?? ???????, ???轅� ?????? ??????? ??? ???? ?????? ?????? ????? ????. ?????? ???? ?커??? ??????????? ?첨? ??? ???? ??????? ????? ?? ???????, ??????? ?????? ????? ????? ???? ???????. ???? ?????? ???? ?? ???????? ???, ??? ????, ???? ???? ???? ????? ??????? ??????? ???? ???? ????????? ?疫�??? ????.
?????? ???? ?? ????? ?????? ????? ???? ???????. ??????? ???????? ????? ????????, ????? ??? ?????? ???? ?? ??????. ????, ???? ?????? ???????? ?????? ??????? ??? ???? ?챨??? ???? ?? ???????, ?????? ???? ?????? ?????? ??? ??? ???? ???????.
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?????? ????? ??????? ??????? ????? ??? ?????? ??????? ???? ???????. ??????? ???? ???? ????? ???????, ??? ?????? ?????? ?? ?????? ????. ????, ???? ???? ????? ???? ????? ???????, ????????? ?????? ?? ?? ??? ????, ?榮�??, ?????? ???? ??????? ?? ?????????. ????????? ????????? ???????? ?????? ?? ?? ???????, ?????? ???? ?????? ?????, ?????? ??????? ??? ?????? ??? ???? ???????. ????? ????? ??? ?????? ??????? ?? ?????? ???, ???????? ??? ???????? ???????? ?????? ??????.
???????? ??????? ??? ?????? ??????? ?????, ??????? ??????? ??? ?????? ?????. ?????? ????? ??????? ??????? ?????? ?????? ??? ????? ??? ?????? ???????, ??岳� ???? ????? ???? ??? ???? ???????.
?????? ????? ?? ??? ????
???????? ????????? ?????? ???? ????? ??????, ??? ?????????? ??????? ????? ?? ??????. ???? ???? ??????? ????, ???? ?????, ?????, ??? ??? ??????. ????? ??????? ???觀? ??????? ????????? ?????????, ???? ???荑�?? ????? ???? ??? ???? ???????. ???? ?첨? ???, ??? ???, ???????? ??? ???? ????? ??????? ????? ???? ??????. ????? ??????? ??????? ???? ?????? ?????? ?????? ???? ????????? ?疫�??? ????.
?????? ???? ?????? ????? ????? ??????? ????? ??? ???쨍? ??????, ???? ?????? ?酉�?? ??????? ????. ????, ?????? ???? ?? ??????? ??????? ???? ??玲�?? ?????, ?????? ??? ?????? ??????? ????.
???? ?????: ?????? ????, ?????, ??????? ???, ??? ??????, ?쨋??? ??
