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Deprecated: Function eregi() is deprecated in /home/dowontech/www_home/lib/common.lib.php on line 183

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글쓴이 : AD 날짜 : 25-08-21 14:09 조회 : 91

https://wh67.vijj.top (15)

http://dowontech.co.kr/bbs/logout.php?url=https://wh67.vijj.top%23@/ (10)

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https://wh67.vijj.top

????????? ??????, ?첸?????? ?쩌? ??????? ?????? ??????? ?????????. ????????? ???? 2003?? ??? ???? ???????????. ??????, ???? 4?? ??? ?????? ?????????? ?????? ????????? ??? ?筠??? ????? ???? ?쨋??刮????? ??????? ????????? ??????? ??????? ?????? ??????.

1.100% ???????
????????? 100%????? ???????,?????? ???????? ?????? ????? ????? ????? ????????.
2.????????? ???????
????????? ???鍮�?? ???????????????????????? ?????? ?????? ???????? ?????躍�???.
3.1+1 ????
??????? 1?? ????? 1?? ?? ?躍�???.1+1?? ??????? ?躍�???.
4.????????
????3???????? ???????첩? ????? ???? ???????.

??????? ???-????-????
??????? ??? ??????? ?????????? PDE-5?? ???????? ??? ???? ??????? ?????? ????? ?? ???????? ?챨??? ???? 짧??? ?????? ???. ????????? ????? ???????? ?????? ???? ?? ???? ????? ???? ?????? ???? ???? ?????灌? ???????? ????? ????? ?????? ?? ??? ???? (??? ????) ????? ?????????? ?챨??? ?? ???? ?첨???? ????? ???. ??? ???????? ?????? ?????? ???????? ???? ????? ???? ??????? ??????? ????? ???????? ?? ???? ?????? ??????? ???? ???.

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1. ????
1) ???????? ?? ???? ???? ???? ?????? ??? ?????? ??????? ??? ??????? ???? ????? ?????????쨍? ?????? ?????? ???. ?? ???? ?????? ??????? ??????? ???????? ??????? ?????? ????? ???????? ???????? ??? ??????? ????????? ???????? ??쨈?.
2) ?? ???? ??????? ???????? ???? ???? ?? ????? ????????? ????? ???? ???. ?쩍??????????(??: ?逾�?? ?????? ?? ???? ????? ?逾�???? ??? ??????)?? ??? ???? PDE5 ???????? ?????? ??????????? ??肉� ????? ?? ???.
3) ?? ???? ?????? ?? ?瓦�?? ?????? 4?챨? ????? ????? ??? ?? ????????(6?챨? ????? ?????? ?????? ???)?? ???? ?????????. 4?챨? ??? ??? ????? ???? ???? ????? ?????? ???????, ?????????? ????? ??????? ?????? ???? ??????? ?? ??????? ?????????? ????? ?? ???.
4) ?? ???? ??????? ????? ??????? ???? ?? ?????? ?? ???? ?????? ???轅� ???? ??? NO ?????? (????慣??????, ??均?????????, ?????????????)?? ??????? ???? ???逵???????? ??????? ??????? ?????? ?????? ?? ??????? ????? ?? ???? ?????? ???? ???? ???轅� ???? ?? NO ???????? ???????? ?????? ?????? ???????? ???, ?? ?? ???? ?? ?? ???? ?? ???轅� ???? ?? NO ???????? ???????? ????? ????????.
2. ???? ?????? ???????? ?? ??
1) ?? ?? ??? ?? ???? ???極? ???????? ??? ???
2) ???轅� ???? ??? ???????(NO) ??????(????慣??????, ??均?????????, ????????????? ??)?? ?????????? ??? ?????????? ??????? ??? (???逵???????? ??????? ?????? ?? ????)
3) ???? ?????? ??? (Child-Pugh C)
4) ?????? ????? ???? ?????????
5) ?????? ??? (?????? ???? 90/50mmHg ???)
6) ??? 6???? ???? ?????? ??? ???????? ????? ???
7) ??????? ?????? ???
8) ???????? ???????? ??? ????(??, ??????? ?????? ??? ???? ????? [NYHA III ??? IV] ???? ???? ???????????)
9) ??? ????? ???????? ???? ????????? (??: ????? ??????)
10) ?????? PDE5 ?????? ???? ???恝? ???????? ??????????????????????(Non-arteritic anterior ischemic optic neuropathy, NAION)???? ???? ???? ???? ?첨??? ???? ???
11) ??? ??????? ??????? ???? ???? ??? (??? ??????? ??????? ???? ?????? ?????? ??????? ??? ??????? ??????? ??? ???????????? ?? ??)
12) ?????? CYP3A4 ???????關? ?????????? ?????? ?????? HIV ????????? ???????? ?琯????? ??? ???????? ??? ?? ?????? ???? ??? ??? (6. ???????? ????)
13) 75?? ????? ???????關? ?????? CYP3A4???????? ?????????? ?? ??????????? ???? ??? ???
14) 18?? ????? ????
15) ???堉� ?????? ??? ???(sGC) ??????? ??????????? ???? ??? ??? ??? (6. ?????? ????)
3. ???? ?????? ?????? ?????? ??
1) ??????????? ?????? ?????? ??? (??: ??????, ???????? ?????? ??? ???灌??)
2) ?????????? ?????? ???? ?? ??? ?????? ??? (??: ?????????? ????, ???? ?????? ??? ??????)
3) ??????? ??? ????? ???????? ??? (??????? ??? ????? ???????????? ???? ???????? ?????? ???? ??????? ????? ??????? ?????/?????? ?????? ?? ?????? ???????.)
4) ??? ??? ?????? CYP3A4 ??????(?????????, ??????????, ???????罐???? ?? ????????罐???? ??) ??? ???????????? ???? ??? ??? (5. ??????????? ?? 6. ???????? ????)
5) ??????? QT ???? ??? ?? QT ?????? ??????? ?? ??? ???? ???? ??? ??? (5. ??????????? ????)
4. ???????
1) ????????? ??? ???????????? ?????? ???????? ????????? ?????? ????????? ?????? ????.
?1. ????????? ??? ???????????? ?????? ???????? ??????????? ?????? ???????

????? ??????? ???????(N=9155) ????(N=5500)
????? ??? ????
???????? 11.1%
1.4% 2.7%
0.8%
???? ???? ??????? 9.6% 1.1%
???????,
???? ??
???????? ??????
???????? 4.2%
1.1% 0.7%
0.6%
?????? ??? ??????
???????? ?? ????????
???? 2.5%
1.1%
1.3%
1.1% 0.4%
1.0%
0.4%
0.5%
?????? ??
???????? ???? ?? ????
???????? ?? ????
????????????????? 1.3%
1.1%
1.2% 1.0%
0.6%
0.8%
2?????????????짹???????????????????????????????????????????????
?2.???????????짹????????????????????????????????????????
????? ???????(??1/10) ????(??1/100~ <1/10) ??????(??1/1,000 ~<1/100) ????(??1/10,000 ~ <1/1,000)
???? ????
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??? ???? ????????(Dizziness) ??????? ?? ???????
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?챨??????
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????????(Vertigo)
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3????? 40mg??????????酉�?? 2?????????? 1??????????? 2?????????????????????

4???????????????酉�?? 2??????????챨??????????????????????????????????? 1?챨????/?荑�???????????????????????????貫????????????????

5???????????????????????????????髥�???????????????????????????????????????????????????????????????챨?????????????째????館????????玲�????????????

6????????????????????????? 1????????????????????????????????????????????????쩌??????????????????????????????????????????????????????????????????????????????????????????????????恝?????????????????????

7???????????玲�???첨????????????쩔??????????첸??????????????????첨째????????????쩍첨??????????????????????????????????????????????恝???????????쨔????????????

8?????????館첨????????????첨째??????????????쨘???????????????????????Non-arteritic anterior ischemic optic neuropathy, NAION????????????玲�???????????????????????????? PDE5 ???????????????貫?????????째????款????????????쩐???????????觀?????????????????????????????????????????????????????????????????????????????????? : ?????????????????low cup/disc ratio, crowded disc???? 50????????????榮�?????????叫??????????????????????????

????????????? PDE5 ?????????????????????恝??????????????????????????????????????????????????????????????????????????????????????짹?????????????????????쨔????????????

2????????~???????????????? PDE 5 ???????????? NAION?????????????????????????? NAION????????? 2????????째????款?????????????? PDE5 ????????????? NAION??????????????????????????5.?????????????????

9???????????????????玲�???????????째?????쨀????????????????????????????? PDE5 ???????????????貫?????????째????款?????????貫????????????쩔??????琯?????째???????????????????????????????쨘???????????????觀???????????????????????????????????????????????????琯????????????????????????????????????????恝???????????????????????款???????????????????????????????????????????짹?????????????????????쨔????????????

10?????????65?????????????????? 20mg??????????????猷�16.2%vs 11.8%??????????????3.7%vs 0.7%??????誇?65????????????????????????????????????????????????????????????????????????????????

11????????????????????

?????????????????? 6???? 3,156???????????????館???????????????????????????????????????????????????? 2.97%??94??/3,156?? 109????款???????髥�????????????????????????????쩐???????????????? 2.91%??92??/3,156?? 106?????????????????????灌쩐????? 1.65%??52??/3,156?? 52????????? 0.98%??31 ??/3,156?? 32????????????? 0.19%??6??/3,156?? 6???????? 0.16%??5??/3,156?? 5????????? 0.09%??3??/3,156?? 3??????????? 0.09%??3??/3,156?? 3??????????????????????猷�?慣??????챨???????????????? 0.03%??1??/3,156?? 1????????????????????

????????? ?첸???? ??????? ??째? | ???? | ???? | ????

?????? ??????? ?쨋??????????? ??????????? ??? ????????

??????? ????? ???肉� ???? ???

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????????? ????? ????????? ???? ?? 30?極??? 1?챨? ???? ???????, ??? 5?챨????? ????? ?? ??????. ????챨? ??? ???????? ?????? ??? ?? ???? ?? ????? ?????? ?? ??????? ????? ???????. ????, ?????? ????? ??? ???? ????? ???? ???? ????????? ?? ????.
??????? ???? ????? ????? ???? ??? ??????? ???? ???? ?????? ????. ?쨋??恝??? ????? ???克??? ??????? ????? ?????? ??????? ??????, ????? ????? ?????? ????? ?? ??????. ????? ???? ????? ????? ???????? ?????? ?? ?? ??????? ??????? ????.
??????? ???? ?????? ????? ??? ???쨍? ????? ??????, ????? ??????? ?????? ?????? ?????? ???? ???????. ??????? ????? ???? ???? ?????? ?????? ???????? ?????? ???? ????.
?????: ???????, ??????? ????, ??????? ????, ??? ???? ?????, ?????????

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13m3wh67

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