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https://onions1.viyy.top
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1. ???????????
???????(erectile dysfunction)???
??????? ?????? ??? ???? ???? ???????? ???? ???쨍? ??????,
????????? ????? ???째? 3???? ??? ???????? ???? ??????????? ????????.
2. ??????? ??????? ????
????????? ????? ??? ????????, ?????????? ??????.
?????灌? ??????? ??? ??? ???? ???? ????
PDE-5 ???????? ?????.
???????灌? ???????? ???? ?????? Alprostadil ???? ??????.
??? ?????? ????? ???? ?? ????? ???罹�?????
3. ??????? ??????? ???? -PDE 5 ??????
PDE0-5 ???????? ??????? ??? ??? 1?? ???? ??????.
????????? ???????? ????.
?? ???? ???????? ???? ?????? ????????? ????? ?????
??????? ?????? ????.
????????? ????????? ???嚥� ??????? ????????? ????
??嚥�?? ???????? ??????? ??? guanylate cyclase?? ??????????.
?????????? cGMP???? ?????? ????? ???????
?? ?????? ???? ????? ??? ???? ?????? ?? ??? ?????.
????????? ????? ???? ?? ????觀??? ???,
?? ??????? ????? ????? ??? ??? ????????? ????? ?????????,
???? ???嚥�?? cGMP?? ????? PDE-5?? ???? ????????.
?????? PDE-5?? ??????? ???嚥�?? cGMP?? ?????? ???? ?????? ?? ???
?? ??? ?????????? ??? ?? ??? ??? ??????.
PDE-5 ?????????灌? Sildenafil(Viagra)?? ????????
???커? ?? ?????? ?????? PDE-5 ????????
Tadalafil(Cialis), Avanafil(Stendra), Vardenafil(Levitra)?? ??????????.
4. ?????? ???????
?????? ????????? ???? ???? ?????? ?????? ????????.
???? ???? ???????? ?? ?????? ???? ?????? ??????,
1?? ???????? ??? ?????? ???? ???? ???? ?????? ?? ???? ??????
???? ???????????? ???????? ???.
sildenafil?? ???????? ??? ??????? ???? ???? ???? ???????
???灌? PGE1 ???????? Alprostadil?? ??????.
?? ???? ???? ???? ???? ???????, ???? ?쩐????쨌? ????
??????? ???? ???????? ?????? ????? ??? ????? ????????.
????, Phentolamine ???? ???? ???? ?????? ?????? ?? ??????.
??????? ????? ???? ?? ?????? ???? ????? ??????! ???????(erectile dysfunction)??? ??????? ?????? ??? ???? ????
???? ??????? ??????? ?????? ???罹�??????. ?????????? ?????????? ??????. ?????灌? ??????? ??? ??? ???? ???? ???? PDE-5 ???????? ?????. ???????灌? ???????? ???? ?????? Alprostadil ???? ??????.
1. PDE 5 ??????
PDE0-5 ???????? ??????? ??? ??? 1?? ???? ??????. ????????? ???????? ?????. ?? ???? ???????? ???? ?????? ????????? ????? ????? ??????? ?????? ????.
2. ??????? ????? ????
????????? ????????? ???嚥� ??????? ????????? ???? ??嚥�?? ???????? ??????? ??? guanylate cyclase?? ??????????. ?????????? cGMP???? ?????? ????? ??????? ?? ?????? ???? ????? ??? ???? ?????? ?? ??? ??????.
3. PDE-5 ???????? ???
????????? ????? ???? ?? ??? ?觀??? ???, ?? ??????? ????? ????? ??? ??? ????????? ????? ?????????, ???? ???嚥�?? cGMP?? ????? PDE-5?? ???? ????????. ?????? PDE-5?? ??????? ???嚥�?? cGMP?? ?????? ???? ?????? ?? ??? ?? ??? ?????????? ??? ?? ??? ??? ??????.
4. PDE-5 ?????? ????
PDE-5 ?????????灌? Sildenafil(Viagra)?? ???????? ???커? ?? ?????? ?????? PDE-5 ???????? Tadalafil(Cialis), Avanafil(Stendra), Vardenafil(Levitra)?? ??????????. ?? ?? Sildenafil?? ??? ????????????關? ??????? ??????, ??? PDE-5 ???????? ?????? ?????? ??????? ??? ????????? ???????.
5. ?????? ???????
?????? ????????? ???? ???? ?????? ?????? ????????. ???? ???? ???????? ???? ???????, ???? ?쩐????쨌? ???? ??????? ???? ???????? ?????? ????? ??? ????? ????????.
6. PGE1 ??????(Alprostadil)
PGE1 ???????? Alprostadil?? ???? ???? ??????? ??????. ?? ???? ???? ???? ???? ???????, ???? ?쩐????쨌? ???? ??????? ???? ???????? ?????? ????? ??? ????? ????????.
7. ???????????
?????? : Eli Lilly
???????????? ??????????
??????????? ??????? ?????? ????? ????? ??????? ????. ?????? ??? ???쩔? ???? ???? ???? ???? ?????? ???酉�?? ????????? ????? ?? ??????. ??? ???????? ????? ???? ???? ???? ???? ???? ???荑�?? ???? ??????? ????.
?????? ???, ???? ?? ???? ?? ????
- ????????Viagra??
???????? ????????????關? ???? ???????? ??????? ??????. ????? ????? ?????? ??????? ????? ?? ??????.
8. ?????? ???? ?? ????? ?? ??? ??????? ??? ????
?????? ???? ?? ????? ?? ??? ??????? ?????? ???????:
- ?????
- ????? ???? ????: ?? ???????? ??????? ?????? ?? ??????.
- ???????? ???: ???????? ???????? ????? ???? ???? ???? ???? ??
?????? ???? ?? ?? ???? ?? ???????
- ???????? ????????
- ???????? ??? ????
- ?????? ???? ?? ???????
- ???????? ??? ???? ?? ??? ??
???????? ?????? ?????? ????? ?????? ???? ????? ????, ?? ?????????? ?罐? ??????? ??????. ?????? ???????? ??????? ?????? ????? ???? ?????? ???????, ?????? ??? ???쨍? ??????? ????.
???????? ??? ?????? ????????, ?????? ??????? ?????? ????????? ?????? ????. ??? ???? ?????? ????? ???????, ??????? ???? ????? ?? ?????? ????. ?????? ???????? ????? ???????? ??????? ???? ????, ????? ??嚥� ???? ??????? ??? ????????.
???????? ?????? ???? ?? ???? ????????? ?? ????? ????. ????, ?????? ????? ??? ???爾� ????慣???????? ???? ???轅� ?瓦� ???? ???? ??????? ?????? ?????? ????? ????. ????, ????? ???? ????? ?????? ??? ???荑�?? ????? ???? ?? ???? ???罐? ??????? ????.
???????? ??? ????? ????????? ??????? ??? ???????. ??????? ??, ???? ???? ???, ?????? ?????? ?????? ?????? ???????? ?????? ??????. ????, ????????? ??????? ????? ????? ?????? ??? ?????? ????.
?????: ??????, ?????? ????, ???????, ???????, ???? ???????
